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Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice

The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study, we report that MALAT1 plays an important role in regulating acute inflammatory responses in sepsis. In patient samples, MA...

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Detalles Bibliográficos
Autores principales:	Chen, Jingshu, Tang, Shu, Ke, Sui, Cai, James J., Osorio, Daniel, Golovko, Andrei, Morpurgo, Benjamin, Guo, Shaodong, Sun, Yuxiang, Winkle, Melanie, Calin, George A., Tian, Yanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241053/ https://www.ncbi.nlm.nih.gov/pubmed/35763934 http://dx.doi.org/10.1016/j.redox.2022.102377

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