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Ru(ii)arene(N^N bpy/phen)-based RAPTA complexes for in vitro anti-tumour activity in human glioblastoma cancer cell lines and in vivo toxicity studies in a zebrafish model
Herein, we have introduced a series of half-sandwich Ru(ii)arene(N^N bpy/phen)-based RAPTA complexes for brain cancer therapy. Among all the synthesized complexes, [(η(6)-p-cymene)Ru(II)(κ(2)-N,N-4,7dimethyl phenanthroline)(PTA)]·2PF(6) (4c) and [(η(6)-p-cymene)Ru(II)(κ(2)-N,N-4,7diphenyl phenanthro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241057/ https://www.ncbi.nlm.nih.gov/pubmed/35873312 http://dx.doi.org/10.1039/d2ra02677e |