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Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo
BACKGROUND: Rapid emergence of Plasmodium resistance to anti-malarial drug mainstays has driven a continual effort to discover novel drugs that target different biochemical pathway (s) during infection. Plasma membrane Calcium + 2 ATPase (PMCA4), a novel plasma membrane protein that regulates Calciu...
Autores principales: | Asih, Puji B. S., Siregar, Josephine E., Dewayanti, Farahana K., Pravitasari, Normalita E., Rozi, Ismail E., Rizki, Andita F. M., Risandi, Rifqi, Couper, Kevin N., Oceandy, Delvac, Syafruddin, Din |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241181/ https://www.ncbi.nlm.nih.gov/pubmed/35768835 http://dx.doi.org/10.1186/s12936-022-04228-0 |
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