Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms

Epigenetic abnormalities in DNA hydroxymethylation (5hmC) have been detected in patients with myeloid neoplasms, suggesting that 5hmC might act as a valuable epigenetic mark to reflect the disease status of myeloid neoplasms. Here, we report systematic genome-wide mapping of the DNA hydroxymethylome...

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Detalles Bibliográficos
Autores principales: Li, Jia, Hong, Tingting, Wei, Yue, Guo, Lei, Lee, Minjung, Yang, Hui, Class, Caleb, Yang, Yaling, Wang, Xiaoqiong, He, Hua, Siwko, Stefan, You, M. James, Zhou, Yubin, Garcia-Manero, Guillermo, Huang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241241/
https://www.ncbi.nlm.nih.gov/pubmed/35765052
http://dx.doi.org/10.1186/s13148-022-01297-5

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