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The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis

BACKGROUND: Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, and ERK-1/2 kinases modulates the function of most of the LH-regulated genes. Defective ERK kinase signaling that is secondary to a genetic problem contributes to both ovulatory dysf...

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Detalles Bibliográficos
Autores principales: Guney, Gurhan, Taşkın, Mine Islimye, Sener, Nazli, Tolu, Ezgi, Dodurga, Yavuz, Elmas, Levent, Cetin, Orkun, Sarigul, Cengiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241270/
https://www.ncbi.nlm.nih.gov/pubmed/35768803
http://dx.doi.org/10.1186/s12958-022-00967-6

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