Identification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo

The capsid (CA) subunit of the HIV-1 Gag polyprotein is involved in several steps of the viral cycle, from the assembly of new viral particles to the protection of the viral genome until it enters into the nucleus of newly infected cells. As such, it represents an interesting therapeutic target to t...

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Detalles Bibliográficos
Autores principales: Alvarez, Guzmán, van Pul, Lisa, Robert, Xavier, Artía, Zoraima, van Nuenen, Ad C., Long, Mathieu, Sierra, Natalia, Porcal, Williams, Kootstra, Neeltje A., Guillon, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241302/
https://www.ncbi.nlm.nih.gov/pubmed/35765101
http://dx.doi.org/10.1186/s40360-022-00581-7

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