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Security breach: peripheral nerves provide unrestricted access for toxin delivery into the central nervous system

We explore the hypothesis that a potential explanation for the initiation of motor neuron disease is an unappreciated vulnerability in central nervous system defense, the direct delivery of neurotoxins into motor neurons via peripheral nerve retrograde transport. This further suggests a mechanism fo...

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Detalles Bibliográficos
Autores principales: Lupinski, Igor, Liang, Allison S., McKinnon, Randall D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241397/
https://www.ncbi.nlm.nih.gov/pubmed/35799510
http://dx.doi.org/10.4103/1673-5374.345472

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