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Security breach: peripheral nerves provide unrestricted access for toxin delivery into the central nervous system
We explore the hypothesis that a potential explanation for the initiation of motor neuron disease is an unappreciated vulnerability in central nervous system defense, the direct delivery of neurotoxins into motor neurons via peripheral nerve retrograde transport. This further suggests a mechanism fo...
Autores principales: | Lupinski, Igor, Liang, Allison S., McKinnon, Randall D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241397/ https://www.ncbi.nlm.nih.gov/pubmed/35799510 http://dx.doi.org/10.4103/1673-5374.345472 |
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