Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes

Neuroinflammation and the NACHT, LRR, and PYD domains-containing protein 3 inflammasome play crucial roles in secondary tissue damage following an initial insult in patients with traumatic brain injury (TBI). Maraviroc, a C-C chemokine receptor type 5 antagonist, has been viewed as a new therapeutic...

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Detalles Bibliográficos
Autores principales: Liu, Xi-Lei, Sun, Dong-Dong, Zheng, Mu-Tian, Li, Xiao-Tian, Niu, Han-Hong, Zhang, Lan, Zhou, Zi-Wei, Rong, Hong-Tao, Wang, Yi, Wang, Ji-Wei, Yang, Gui-Li, Liu, Xiao, Chen, Fang-Lian, Zhou, Yuan, Zhang, Shu, Zhang, Jian-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241405/
https://www.ncbi.nlm.nih.gov/pubmed/35799534
http://dx.doi.org/10.4103/1673-5374.344829

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