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Dysregulated expression and distribution of Kif5α in neurites of wobbler motor neurons

Impaired axonal transport has been observed in patients with amyotrophic lateral sclerosis (ALS) and in animal models, suggesting that transport proteins likely play a critical role in the pathological mechanism of ALS. Dysregulation of Kinesin-family-member 5α (Kif5α), a neuron-specific isoform of...

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Detalles Bibliográficos
Autores principales: Kürten, Kilian, Gude, Anne-Christin, Epplen, Aimo Samuel Christian, Stein, Jan, Theiss, Carsten, Matschke, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241431/
https://www.ncbi.nlm.nih.gov/pubmed/35799535
http://dx.doi.org/10.4103/1673-5374.343883