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High Serum Vitamin D Concentrations, Induced via Diet, Trigger Immune and Intestinal Microbiota Alterations Leading to Type 1 Diabetes Protection in NOD Mice

The hormonally-active form of vitamin D, 1,25-dihydroxyvitamin D(3), can modulate both innate and adaptive immunity, through binding to the nuclear vitamin D receptor expressed in most immune cells. A high dose of regular vitamin D protected non-obese diabetic (NOD) mice against type 1 diabetes (T1D...

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Detalles Bibliográficos
Autores principales:	Martens, Pieter-Jan, Centelles-Lodeiro, Javier, Ellis, Darcy, Cook, Dana Paulina, Sassi, Gabriele, Verlinden, Lieve, Verstuyf, Annemieke, Raes, Jeroen, Mathieu, Chantal, Gysemans, Conny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241442/ https://www.ncbi.nlm.nih.gov/pubmed/35784365 http://dx.doi.org/10.3389/fimmu.2022.902678

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