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Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania

In mammalian cells, DNA double-strand breaks (DSBs) are mainly repaired by nonhomologous end joining (NHEJ) pathway. Ku (a heterodimer formed by Ku70 and Ku80 proteins) and DNA ligase IV are the core NHEJ factors. Ku could also be involved in other cellular processes, including telomere length regul...

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Detalles Bibliográficos
Autores principales:	Zhang, Wen-Wei, Wright, Douglas G., Harrison, Lynn, Matlashewski, Greg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241504/ https://www.ncbi.nlm.nih.gov/pubmed/35695492 http://dx.doi.org/10.1128/msphere.00156-22

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