Strain Variation in Clostridioides difficile Cytotoxicity Associated with Genomic Variation at Both Pathogenic and Nonpathogenic Loci

Clinical disease from Clostridioides difficile infection can be mediated by two toxins and their neighboring regulatory genes located within the five-gene pathogenicity locus (PaLoc). We provide several lines of evidence that the cytotoxicity of C. difficile may be modulated by genomic variants outs...

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Detalles Bibliográficos
Autores principales: Saund, Katie, Pirani, Ali, Lacy, D. Borden, Hanna, Philip C., Snitkin, Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241522/
https://www.ncbi.nlm.nih.gov/pubmed/35766503
http://dx.doi.org/10.1128/msphere.00174-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241522/
https://www.ncbi.nlm.nih.gov/pubmed/35766503
http://dx.doi.org/10.1128/msphere.00174-22

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