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Electrostatic Interaction with the Bacterial Cell Envelope Tunes the Lytic Activity of Two Novel Peptidoglycan Hydrolases
Peptidoglycan (PG) hydrolases, due to their crucial role in the metabolism of the bacterial cell wall (CW), are increasingly being considered suitable targets for therapies, and a potent alternative to conventional antibiotics. In the light of contradictory data reported, detailed mechanism of regul...
Autores principales: | Wysocka, Alicja, Łężniak, Łukasz, Jagielska, Elżbieta, Sabała, Izabela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241647/ https://www.ncbi.nlm.nih.gov/pubmed/35467396 http://dx.doi.org/10.1128/spectrum.00455-22 |
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