Cefotaxime Exposure Selects Mutations within the CA-Domain of envZ Which Promote Antibiotic Resistance but Repress Biofilm Formation in Salmonella

Cephalosporins are important beta lactam antibiotics, but resistance can be mediated by various mechanisms including production of beta lactamase enzymes, changes in membrane permeability or active efflux. We used an evolution model to study how Salmonella adapts to subinhibitory concentrations of c...

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Detalles Bibliográficos
Autores principales: Trampari, Eleftheria, Zhang, Chuanzhen, Gotts, Kathryn, Savva, George M., Bavro, Vassiliy N., Webber, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241649/
https://www.ncbi.nlm.nih.gov/pubmed/35475640
http://dx.doi.org/10.1128/spectrum.02145-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241649/
https://www.ncbi.nlm.nih.gov/pubmed/35475640
http://dx.doi.org/10.1128/spectrum.02145-21

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