Japanese Encephalitis Virus NS4A Protein Interacts with PTEN-Induced Kinase 1 (PINK1) and Promotes Mitophagy in Infected Cells

The nonstructural protein 4A (NS4A) of flaviviruses has been implicated as a “central organizer” of the membrane-bound replication complex during virus replication. However, its role in the host responses to virus infection is not understood. Using the yeast-two-hybrid library screen, we identified...

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Detalles Bibliográficos
Autores principales: Agarwal, Anshu, Alam, Mohd. Faraz, Basu, Brohmomoy, Pattanayak, Sabyasachi, Asthana, Shailendra, Syed, Gulam Hussain, Kalia, Manjula, Vrati, Sudhanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241661/
https://www.ncbi.nlm.nih.gov/pubmed/35604158
http://dx.doi.org/10.1128/spectrum.00830-22

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