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Single-Cell Profiling of Latently SIV-Infected CD4(+) T Cells Directly Ex Vivo to Reveal Host Factors Supporting Reservoir Persistence

HIV-1 cure strategies aiming to eliminate persistent infected cell reservoirs are hampered by a poor understanding of cells harboring viral DNA in vivo. We describe a novel method to identify, enumerate, and characterize in detail individual cells infected in vivo using a combination of single-cell...

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Detalles Bibliográficos
Autores principales:	Tokarev, Andrey, Machmach, Kawthar, Creegan, Matthew, Kim, Dohoon, Eller, Michael A., Bolton, Diane L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241701/ https://www.ncbi.nlm.nih.gov/pubmed/35510859 http://dx.doi.org/10.1128/spectrum.00604-22

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