Gut Microbiota of Obese Children Influences Inflammatory Mucosal Immune Pathways in the Respiratory Tract to Influenza Virus Infection: Optimization of an Ideal Duration of Microbial Colonization in a Gnotobiotic Pig Model

The impact of obesity on the human microbiota, immune maturation, and influenza virus infection has not been yet established in natural host animal models of influenza. In this study, gnotobiotic (Gn) pigs were colonized with human fecal microbiota (HFM) of obese (oHFM) or healthy lean (hHFM) childr...

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Detalles Bibliográficos
Autores principales: Renu, Sankar, Deblais, Loic, Patil, Veerupaxagouda, Schrock, Jennifer, Kathayat, Dipak, Srivastava, Vishal, Feliciano-Ruiz, Ninoshkaly, Han, Yi, Ramesh, Anikethana, Lakshmanappa, Yashavanth S., Ghimire, Shristi, Dhakal, Santosh, Rajashekara, Gireesh, Renukaradhya, Gourapura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241774/
https://www.ncbi.nlm.nih.gov/pubmed/35579462
http://dx.doi.org/10.1128/spectrum.02674-21

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