Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene

Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC. However, whether specific mutations induced by ETBF lead to colon tumor formation has no...

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Detalles Bibliográficos
Autores principales: Allen, Jawara, Rosendahl Huber, Axel, Pleguezuelos-Manzano, Cayetano, Puschhof, Jens, Wu, Shaoguang, Wu, Xinqun, Boot, Charelle, Saftien, Aurelia, O’Hagan, Heather M., Wang, Hao, van Boxtel, Ruben, Clevers, Hans, Sears, Cynthia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241831/
https://www.ncbi.nlm.nih.gov/pubmed/35587635
http://dx.doi.org/10.1128/spectrum.01055-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241831/
https://www.ncbi.nlm.nih.gov/pubmed/35587635
http://dx.doi.org/10.1128/spectrum.01055-22

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