Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoonotic agent capable of infecting humans and a wide range of animal species. Over the duration of the pandemic, mutations in the SARS-CoV-2 spike (S) protein have arisen, culminating in the spread of several variants of concern (VOC...

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Autores principales: Kim, Yunjeong, Gaudreault, Natasha N., Meekins, David A., Perera, Krishani D., Bold, Dashzeveg, Trujillo, Jessie D., Morozov, Igor, McDowell, Chester D., Chang, Kyeong-Ok, Richt, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241865/
https://www.ncbi.nlm.nih.gov/pubmed/35638818
http://dx.doi.org/10.1128/spectrum.01789-21

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