The AAV-PCSK9 murine model of atherosclerosis and metabolic dysfunction

AIMS: Mouse models with genetic modifications are required to investigate atherogenesis and associated metabolic syndrome. Adeno-associated virus-8 (AAV8)-mediated overexpression of PCSK9 (AAV8-PCSK9) induces hyperlipidaemia and promotes atherosclerosis in C57BL/6 mice. We aimed to assess whether AA...

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Detalles Bibliográficos
Autores principales: Keeter, William Coles, Carter, Nigeste M, Nadler, Jerry L, Galkina, Elena V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242032/
https://www.ncbi.nlm.nih.gov/pubmed/35919346
http://dx.doi.org/10.1093/ehjopen/oeac028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242032/
https://www.ncbi.nlm.nih.gov/pubmed/35919346
http://dx.doi.org/10.1093/ehjopen/oeac028

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