Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4

Both SIV and SHIV are powerful tools for evaluating antibody-mediated prevention and treatment of HIV-1. However, owing to a lack of rhesus-derived SIV broadly neutralizing antibodies (bnAbs), testing of bnAbs for HIV-1 prevention or treatment has thus far been performed exclusively in the SHIV NHP...

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Detalles Bibliográficos
Autores principales: Welles, Hugh C., King, Hannah A. D., Nettey, Leonard, Cavett, Nicole, Gorman, Jason, Zhou, Tongqing, Tsybovsky, Yaroslav, Du, Renguang, Song, Kaimei, Nguyen, Richard, Ambrozak, David, Ransier, Amy, Schramm, Chaim A., Doria-Rose, Nicole A., Swanstrom, Adrienne E., Hoxie, James A., LaBranche, Celia, Montefiori, David C., Douek, Daniel C., Kwong, Peter D., Mascola, John R., Roederer, Mario, Mason, Rosemarie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242510/
https://www.ncbi.nlm.nih.gov/pubmed/35709309
http://dx.doi.org/10.1371/journal.ppat.1010574

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