Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus

Akkermansia muciniphila is a promising gut microbiota for the treatment of type 2 diabetes mellitus (T2DM). A. muciniphila stimulates intestinal wall integrity, is an anti-inflammatory agent, and reduces endoplasmic reticulum stress, lipogenesis and gluconeogenesis. These properties make A. muciniph...

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Detalles Bibliográficos
Autores principales: Sanjiwani, Made Indira Dianti, Aryadi, I Putu Hendri, Semadi, I Made Siswadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242659/
https://www.ncbi.nlm.nih.gov/pubmed/35800592
http://dx.doi.org/10.15605/jafes.037.01.13
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author Sanjiwani, Made Indira Dianti
Aryadi, I Putu Hendri
Semadi, I Made Siswadi
author_facet Sanjiwani, Made Indira Dianti
Aryadi, I Putu Hendri
Semadi, I Made Siswadi
author_sort Sanjiwani, Made Indira Dianti
collection PubMed
description Akkermansia muciniphila is a promising gut microbiota for the treatment of type 2 diabetes mellitus (T2DM). A. muciniphila stimulates intestinal wall integrity, is an anti-inflammatory agent, and reduces endoplasmic reticulum stress, lipogenesis and gluconeogenesis. These properties make A. muciniphila a potential treatment option for T2DM by reducing insulin resistance and increasing insulin sensitivity and glucose tolerance in different tissues. This article explores the possible role of A. muciniphila in T2DM management, along with the various methods known to modulate A. muciniphila.
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spelling pubmed-92426592022-07-06 Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus Sanjiwani, Made Indira Dianti Aryadi, I Putu Hendri Semadi, I Made Siswadi J ASEAN Fed Endocr Soc Review Article Akkermansia muciniphila is a promising gut microbiota for the treatment of type 2 diabetes mellitus (T2DM). A. muciniphila stimulates intestinal wall integrity, is an anti-inflammatory agent, and reduces endoplasmic reticulum stress, lipogenesis and gluconeogenesis. These properties make A. muciniphila a potential treatment option for T2DM by reducing insulin resistance and increasing insulin sensitivity and glucose tolerance in different tissues. This article explores the possible role of A. muciniphila in T2DM management, along with the various methods known to modulate A. muciniphila. Journal of the ASEAN Federation of Endocrine Societies 2022-04-21 2022 /pmc/articles/PMC9242659/ /pubmed/35800592 http://dx.doi.org/10.15605/jafes.037.01.13 Text en © 2022 Journal of the ASEAN Federation of Endocrine Societies https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Review Article
Sanjiwani, Made Indira Dianti
Aryadi, I Putu Hendri
Semadi, I Made Siswadi
Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title_full Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title_fullStr Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title_full_unstemmed Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title_short Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus
title_sort review of literature on akkermansia muciniphila and its possible role in the etiopathogenesis and therapy of type 2 diabetes mellitus
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242659/
https://www.ncbi.nlm.nih.gov/pubmed/35800592
http://dx.doi.org/10.15605/jafes.037.01.13
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