Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report

We report a case of a 24-year-old Filipino male who complained of general weakness, polydipsia, weight loss, bitemporal headaches, loss of libido and behavioral changes. Endocrine work-up revealed neurogenic diabetes insipidus and panhypopituitarism. Brain MRI showed multiple intracranial tumors in...

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Autores principales: Gan, Florence Rochelle, Gomez, Maria Honolina, Tapispisan, Julie Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242662/
https://www.ncbi.nlm.nih.gov/pubmed/35800587
http://dx.doi.org/10.15605/jafes.037.01.12
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author Gan, Florence Rochelle
Gomez, Maria Honolina
Tapispisan, Julie Ann
author_facet Gan, Florence Rochelle
Gomez, Maria Honolina
Tapispisan, Julie Ann
author_sort Gan, Florence Rochelle
collection PubMed
description We report a case of a 24-year-old Filipino male who complained of general weakness, polydipsia, weight loss, bitemporal headaches, loss of libido and behavioral changes. Endocrine work-up revealed neurogenic diabetes insipidus and panhypopituitarism. Brain MRI showed multiple intracranial tumors in the left frontal lobe, pineal and suprasellar region with moderate non-communicating hydrocephalus. Intracranial mass biopsy with ventriculo-peritoneal shunting was done. Histopathology of the mass and CSF revealed a germinoma. He underwent chemoradiotherapy while on maintenance hormone replacement.
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spelling pubmed-92426622022-07-06 Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report Gan, Florence Rochelle Gomez, Maria Honolina Tapispisan, Julie Ann J ASEAN Fed Endocr Soc Case Report We report a case of a 24-year-old Filipino male who complained of general weakness, polydipsia, weight loss, bitemporal headaches, loss of libido and behavioral changes. Endocrine work-up revealed neurogenic diabetes insipidus and panhypopituitarism. Brain MRI showed multiple intracranial tumors in the left frontal lobe, pineal and suprasellar region with moderate non-communicating hydrocephalus. Intracranial mass biopsy with ventriculo-peritoneal shunting was done. Histopathology of the mass and CSF revealed a germinoma. He underwent chemoradiotherapy while on maintenance hormone replacement. Journal of the ASEAN Federation of Endocrine Societies 2022-05-13 2022 /pmc/articles/PMC9242662/ /pubmed/35800587 http://dx.doi.org/10.15605/jafes.037.01.12 Text en © 2022 Journal of the ASEAN Federation of Endocrine Societies https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Case Report
Gan, Florence Rochelle
Gomez, Maria Honolina
Tapispisan, Julie Ann
Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title_full Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title_fullStr Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title_full_unstemmed Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title_short Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report
title_sort treatment outcome of a β-hcg secreting intracranial germ cell tumor in an adult filipino using definitive chemotherapy followed by radiotherapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242662/
https://www.ncbi.nlm.nih.gov/pubmed/35800587
http://dx.doi.org/10.15605/jafes.037.01.12
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