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Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype

Noncoding RNAs are important regulators of mucoinflammatory response, but little is known about the contribution of airway long noncoding RNAs (lncRNAs) in COVID-19. RNA-seq analysis showed a more than 4-fold increased expression of IL-6, ICAM-1, CXCL-8, and SCGB1A1 inflammatory factors; MUC5AC and ...

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Detalles Bibliográficos
Autores principales:	Devadoss, Dinesh, Acharya, Arpan, Manevski, Marko, Houserova, Dominika, Cioffi, Michael D., Pandey, Kabita, Nair, Madhavan, Chapagain, Prem, Mirsaeidi, Mehdi, Borchert, Glen M., Byrareddy, Siddappa N., Chand, Hitendra S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242679/ https://www.ncbi.nlm.nih.gov/pubmed/35789750 http://dx.doi.org/10.1016/j.isci.2022.104685

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