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Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion

Despite significant improvements in treatment and survival in paediatric cancers, outcomes for children with brain tumours remain poor. Novel therapeutic approaches are needed to improve survival and quality of survival. Extracellular arginine dependency (auxotrophy) has been recognised in several t...

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Detalles Bibliográficos
Autores principales:	Bishop, Eleanor, Dimitrova, Monika, Froggatt, Alexander, Estevez-Cebrero, Maria, Storer, Lisa C. D., Mussai, Francis, Paine, Simon, Grundy, Richard G., Dandapani, Madhumita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242779/ https://www.ncbi.nlm.nih.gov/pubmed/35782058 http://dx.doi.org/10.1155/2022/9008685

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