Cargando…

Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia

Although the prevalence of hereditary hemolytic anemia (HHA) is relatively low in Korea, it has been gradually increasing in recent decades due to increment in the proportions of hemoglobinopathies from immigrants of South East Asia, raising awareness of the disease among clinicians, and advances in...

Descripción completa

Detalles Bibliográficos
Autores principales: Chueh, Hee Won, Hwang, Sang Mee, Shim, Ye Jee, Lee, Jae Min, Park, Hee Sue, Lee, Joon Hee, Nam, Youngwon, Kim, Namhee, Jung, Hye Lim, Choi, Hyoung Soo, Party, on behalf of Korean RBC Disorder Working
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242826/
https://www.ncbi.nlm.nih.gov/pubmed/35593002
http://dx.doi.org/10.5045/br.2022.2021224
_version_ 1784738140590702592
author Chueh, Hee Won
Hwang, Sang Mee
Shim, Ye Jee
Lee, Jae Min
Park, Hee Sue
Lee, Joon Hee
Nam, Youngwon
Kim, Namhee
Jung, Hye Lim
Choi, Hyoung Soo
Party, on behalf of Korean RBC Disorder Working
author_facet Chueh, Hee Won
Hwang, Sang Mee
Shim, Ye Jee
Lee, Jae Min
Park, Hee Sue
Lee, Joon Hee
Nam, Youngwon
Kim, Namhee
Jung, Hye Lim
Choi, Hyoung Soo
Party, on behalf of Korean RBC Disorder Working
author_sort Chueh, Hee Won
collection PubMed
description Although the prevalence of hereditary hemolytic anemia (HHA) is relatively low in Korea, it has been gradually increasing in recent decades due to increment in the proportions of hemoglobinopathies from immigrants of South East Asia, raising awareness of the disease among clinicians, and advances in diagnostic technology. As such, the red blood cell (RBC) Disorder Working Party (WP), previously called HHA WP, of the Korean Society of Hematology (KSH) developed the Korean Standard Operating Procedures (SOPs) for the diagnosis of HHA in 2007. These SOPs have been continuously revised and updated following advances in diagnostic technology [e.g., flow cytometric osmotic fragility test (FOFT) and eosin-5-maleimide (EMA) binding test], current methods for membrane protein or enzyme analysis [e.g., liquid chromatography-tandem mass spectrometry (LC-MS/MS), ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), high-performance liquid chromatography (HPLC)], and molecular genetic tests using next-generation sequencing (NGS). However, the diagnosis and treatment of HHA remain challenging as they require considerable experience and understanding of the disease. Therefore, in this new Korean Clinical Practice Guidelines for the Diagnosis of HHA, on behalf of the RBC Disorder WP of KSH, updated guidelines to approach patients suspected of HHA are summarized. NGS is proposed to perform prior to membrane protein or enzyme analysis by LC-MS/MS, UPLC-MS/MS or HPLC techniques due to the availability of gene testing in more laboratories in Korea. We hope that this guideline will be helpful for clinicians in making diagnostic decisions for patients with HHA in Korea.
format Online
Article
Text
id pubmed-9242826
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis
record_format MEDLINE/PubMed
spelling pubmed-92428262022-07-13 Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia Chueh, Hee Won Hwang, Sang Mee Shim, Ye Jee Lee, Jae Min Park, Hee Sue Lee, Joon Hee Nam, Youngwon Kim, Namhee Jung, Hye Lim Choi, Hyoung Soo Party, on behalf of Korean RBC Disorder Working Blood Res Review Article Although the prevalence of hereditary hemolytic anemia (HHA) is relatively low in Korea, it has been gradually increasing in recent decades due to increment in the proportions of hemoglobinopathies from immigrants of South East Asia, raising awareness of the disease among clinicians, and advances in diagnostic technology. As such, the red blood cell (RBC) Disorder Working Party (WP), previously called HHA WP, of the Korean Society of Hematology (KSH) developed the Korean Standard Operating Procedures (SOPs) for the diagnosis of HHA in 2007. These SOPs have been continuously revised and updated following advances in diagnostic technology [e.g., flow cytometric osmotic fragility test (FOFT) and eosin-5-maleimide (EMA) binding test], current methods for membrane protein or enzyme analysis [e.g., liquid chromatography-tandem mass spectrometry (LC-MS/MS), ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), high-performance liquid chromatography (HPLC)], and molecular genetic tests using next-generation sequencing (NGS). However, the diagnosis and treatment of HHA remain challenging as they require considerable experience and understanding of the disease. Therefore, in this new Korean Clinical Practice Guidelines for the Diagnosis of HHA, on behalf of the RBC Disorder WP of KSH, updated guidelines to approach patients suspected of HHA are summarized. NGS is proposed to perform prior to membrane protein or enzyme analysis by LC-MS/MS, UPLC-MS/MS or HPLC techniques due to the availability of gene testing in more laboratories in Korea. We hope that this guideline will be helpful for clinicians in making diagnostic decisions for patients with HHA in Korea. Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2022-06-30 2022-06-30 /pmc/articles/PMC9242826/ /pubmed/35593002 http://dx.doi.org/10.5045/br.2022.2021224 Text en © 2022 Korean Society of Hematology https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chueh, Hee Won
Hwang, Sang Mee
Shim, Ye Jee
Lee, Jae Min
Park, Hee Sue
Lee, Joon Hee
Nam, Youngwon
Kim, Namhee
Jung, Hye Lim
Choi, Hyoung Soo
Party, on behalf of Korean RBC Disorder Working
Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title_full Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title_fullStr Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title_full_unstemmed Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title_short Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
title_sort korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242826/
https://www.ncbi.nlm.nih.gov/pubmed/35593002
http://dx.doi.org/10.5045/br.2022.2021224
work_keys_str_mv AT chuehheewon koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT hwangsangmee koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT shimyejee koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT leejaemin koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT parkheesue koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT leejoonhee koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT namyoungwon koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT kimnamhee koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT junghyelim koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT choihyoungsoo koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia
AT partyonbehalfofkoreanrbcdisorderworking koreanclinicalpracticeguidelinesforthediagnosisofhereditaryhemolyticanemia