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From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model

There are five different forms of intervention presently realised by the Indonesian government in an effort to end the COVID-19 pandemic: vaccinations, social restrictions, tracings, testings, and treatments. In this paper, we construct a mathematical model of type SVEIQHR (susceptible-vaccinated-ex...

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Autores principales: Yong, Benny, Hoseana, Jonathan, Owen, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242893/
https://www.ncbi.nlm.nih.gov/pubmed/35789595
http://dx.doi.org/10.1016/j.idm.2022.06.004
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author Yong, Benny
Hoseana, Jonathan
Owen, Livia
author_facet Yong, Benny
Hoseana, Jonathan
Owen, Livia
author_sort Yong, Benny
collection PubMed
description There are five different forms of intervention presently realised by the Indonesian government in an effort to end the COVID-19 pandemic: vaccinations, social restrictions, tracings, testings, and treatments. In this paper, we construct a mathematical model of type SVEIQHR (susceptible-vaccinated-exposed-infected-quarantined-hospitalised-recovered) for the disease's spread in the country, which incorporates as parameters the rates of the above interventions, as well as the vaccine's efficacy. We determine the model's equilibria and basic reproduction number. Using the model, we formulate strategies by which the interventions should be realised in order to optimise their impact. The results show that, in a disease-free state, when the number of new cases rises, the best strategy is to implement social restrictions, whereas in an endemic state, if a near-lockdown policy is undesirable, carrying out vaccinations is the best strategy; however, efforts should be aimed not primarily towards increasing the vaccination rate, but towards the use of high-efficacy vaccines.
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spelling pubmed-92428932022-06-30 From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model Yong, Benny Hoseana, Jonathan Owen, Livia Infect Dis Model Original Research Article There are five different forms of intervention presently realised by the Indonesian government in an effort to end the COVID-19 pandemic: vaccinations, social restrictions, tracings, testings, and treatments. In this paper, we construct a mathematical model of type SVEIQHR (susceptible-vaccinated-exposed-infected-quarantined-hospitalised-recovered) for the disease's spread in the country, which incorporates as parameters the rates of the above interventions, as well as the vaccine's efficacy. We determine the model's equilibria and basic reproduction number. Using the model, we formulate strategies by which the interventions should be realised in order to optimise their impact. The results show that, in a disease-free state, when the number of new cases rises, the best strategy is to implement social restrictions, whereas in an endemic state, if a near-lockdown policy is undesirable, carrying out vaccinations is the best strategy; however, efforts should be aimed not primarily towards increasing the vaccination rate, but towards the use of high-efficacy vaccines. KeAi Publishing 2022-06-30 /pmc/articles/PMC9242893/ /pubmed/35789595 http://dx.doi.org/10.1016/j.idm.2022.06.004 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Yong, Benny
Hoseana, Jonathan
Owen, Livia
From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title_full From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title_fullStr From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title_full_unstemmed From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title_short From pandemic to a new normal: Strategies to optimise governmental interventions in Indonesia based on an SVEIQHR-type mathematical model
title_sort from pandemic to a new normal: strategies to optimise governmental interventions in indonesia based on an sveiqhr-type mathematical model
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242893/
https://www.ncbi.nlm.nih.gov/pubmed/35789595
http://dx.doi.org/10.1016/j.idm.2022.06.004
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