IFN-γ(+) cytotoxic CD4(+) T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40

The food colorant Red 40 is an environmental risk factor for colitis development in mice with increased expression of interleukin (IL)-23. This immune response is mediated by CD4(+) T cells, but mechanistic insights into how these CD4(+) T cells trigger and perpetuate colitis have remained elusive....

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Detalles Bibliográficos
Autores principales: Chen, Lili, He, Zhengxiang, Reis, Bernardo S., Gelles, Jesse D., Chipuk, Jerry Edward, Ting, Adrian T., Spicer, Julie A., Trapani, Joseph A., Furtado, Glaucia C., Lira, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243055/
https://www.ncbi.nlm.nih.gov/pubmed/35468944
http://dx.doi.org/10.1038/s41423-022-00864-3

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