Cargando…
The kinase p38α functions in dendritic cells to regulate Th2-cell differentiation and allergic inflammation
Dendritic cells (DCs) play a critical role in controlling T helper 2 (Th2) cell-dependent diseases, but the signaling mechanism that triggers this function is not fully understood. We showed that p38α activity in DCs was decreased upon HDM stimulation and dynamically regulated by both extrinsic sign...
Autores principales: | Han, Miaomiao, Ma, Jingyu, Ouyang, Suidong, Wang, Yanyan, Zheng, Tingting, Lu, Peishan, Zheng, Zihan, Zhao, Weiheng, Li, Hongjin, Wu, Yun, Zhang, Baohua, Hu, Ran, Otsu, Kinya, Liu, Xinguang, Wan, Ying, Li, Huabin, Huang, Gonghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243149/ https://www.ncbi.nlm.nih.gov/pubmed/35551270 http://dx.doi.org/10.1038/s41423-022-00873-2 |
Ejemplares similares
-
p38α signaling programs dendritic cells to drive T(H)17 cell differentiation and autoimmune inflammation
por: Huang, Gonghua, et al.
Publicado: (2012) -
Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation
por: Han, Miaomiao, et al.
Publicado: (2018) -
MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease
por: Zhao, Weiheng, et al.
Publicado: (2018) -
Berberine-Loaded Biomimetic Nanoparticles Attenuate Inflammation of Experimental Allergic Asthma via Enhancing IL-12 Expression
por: Jin, Hua, et al.
Publicado: (2021) -
Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling
por: Kase, Yoshitaka, et al.
Publicado: (2019)