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Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids

OBJECTIVE: Mitochondrial capacity is critical to adapt the high energy demand of the heart to circadian oscillations and diseased states. Glucocorticoids regulate the circadian cycle of energy metabolism, but little is known about how circadian timing of exogenous glucocorticoid dosing directly regu...

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Detalles Bibliográficos
Autores principales: Wintzinger, Michelle, Panta, Manoj, Miz, Karen, Prabakaran, Ashok D., Durumutla, Hima Bindu, Sargent, Michelle, Peek, Clara Bien, Bass, Joseph, Molkentin, Jeffery D., Quattrocelli, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243158/
https://www.ncbi.nlm.nih.gov/pubmed/35717025
http://dx.doi.org/10.1016/j.molmet.2022.101528

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