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Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids
OBJECTIVE: Mitochondrial capacity is critical to adapt the high energy demand of the heart to circadian oscillations and diseased states. Glucocorticoids regulate the circadian cycle of energy metabolism, but little is known about how circadian timing of exogenous glucocorticoid dosing directly regu...
Autores principales: | Wintzinger, Michelle, Panta, Manoj, Miz, Karen, Prabakaran, Ashok D., Durumutla, Hima Bindu, Sargent, Michelle, Peek, Clara Bien, Bass, Joseph, Molkentin, Jeffery D., Quattrocelli, Mattia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243158/ https://www.ncbi.nlm.nih.gov/pubmed/35717025 http://dx.doi.org/10.1016/j.molmet.2022.101528 |
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