E-cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme

BACKGROUND: E-cigarette aerosol containing aldehydes, including acetaldehyde, are metabolized by the enzyme aldehyde dehydrogenase 2 (ALDH2). However, little is known how aldehyde exposure from e-cigarettes, when coupled with an inactivating ALDH2 genetic variant, ALDH2*2 (present in 8% of the world...

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Detalles Bibliográficos
Autores principales: Yu, Xuan, Zeng, Xiaocong, Xiao, Feng, Chen, Ri, Sinharoy, Pritam, Gross, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243159/
https://www.ncbi.nlm.nih.gov/pubmed/35751982
http://dx.doi.org/10.1016/j.redox.2022.102369

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