Identification and Analysis of Six Phosphorylation Sites Within the Xenopus laevis Linker Histone H1.0 C-Terminal Domain Indicate Distinct Effects on Nucleosome Structure

As a key structural component of the chromatin of higher eukaryotes, linker histones (H1s) are involved in stabilizing the folding of extended nucleosome arrays into higher-order chromatin structures and function as a gene-specific regulator of transcription in vivo. The H1 C-terminal domain (CTD) i...

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Detalles Bibliográficos
Autores principales: Hao, Fanfan, Mishra, Laxmi N., Jaya, Prasoon, Jones, Richard, Hayes, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243160/
https://www.ncbi.nlm.nih.gov/pubmed/35618225
http://dx.doi.org/10.1016/j.mcpro.2022.100250

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