mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine

Methionine adenosyltransferase (MAT) catalyzes the synthesis of S-adenosylmethionine (SAM). As the sole methyl-donor for methylation of DNA, RNA, and proteins, SAM levels affect gene expression by changing methylation patterns. Expression of MAT2A, the catalytic subunit of isozyme MAT2, is positivel...

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Detalles Bibliográficos
Autores principales: Alam, Mahabub, Shima, Hiroki, Matsuo, Yoshitaka, Long, Nguyen Chi, Matsumoto, Mitsuyo, Ishii, Yusho, Sato, Nichika, Sugiyama, Takato, Nobuta, Risa, Hashimoto, Satoshi, Liu, Liang, Kaneko, Mika K., Kato, Yukinari, Inada, Toshifumi, Igarashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243181/
https://www.ncbi.nlm.nih.gov/pubmed/35636512
http://dx.doi.org/10.1016/j.jbc.2022.102084

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