The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine

MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function...

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Detalles Bibliográficos
Autores principales: Li, Yin, Zhang, Yihan, Zou, Yuhao, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243315/
https://www.ncbi.nlm.nih.gov/pubmed/35782974
http://dx.doi.org/10.1016/j.gendis.2020.09.007
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author Li, Yin
Zhang, Yihan
Zou, Yuhao
Duan, Shiwei
author_facet Li, Yin
Zhang, Yihan
Zou, Yuhao
Duan, Shiwei
author_sort Li, Yin
collection PubMed
description MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function of inhibiting cancer. At the same time, the expression of miR-4295 is related to prognosis and can be affected by numerous factors connecting to the therapeutic effects of various drugs. This article is to better summarize the role of miR-4295 in cancer and review the potential diagnostic, prognostic, and therapeutic value of miR-4295, which may provide insight into subsequent research.
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spelling pubmed-92433152022-07-01 The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine Li, Yin Zhang, Yihan Zou, Yuhao Duan, Shiwei Genes Dis Review Article MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function of inhibiting cancer. At the same time, the expression of miR-4295 is related to prognosis and can be affected by numerous factors connecting to the therapeutic effects of various drugs. This article is to better summarize the role of miR-4295 in cancer and review the potential diagnostic, prognostic, and therapeutic value of miR-4295, which may provide insight into subsequent research. Chongqing Medical University 2020-10-06 /pmc/articles/PMC9243315/ /pubmed/35782974 http://dx.doi.org/10.1016/j.gendis.2020.09.007 Text en © 2020 Chongqing Medical University. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Li, Yin
Zhang, Yihan
Zou, Yuhao
Duan, Shiwei
The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title_full The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title_fullStr The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title_full_unstemmed The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title_short The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
title_sort paradoxical roles of mir-4295 in human cancer: implications in pathogenesis and personalized medicine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243315/
https://www.ncbi.nlm.nih.gov/pubmed/35782974
http://dx.doi.org/10.1016/j.gendis.2020.09.007
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