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Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth

Glioblastoma (GBM, WHO grade IV glioma) is the most common and lethal malignant brain tumor in adults with a dismal prognosis. The extracellular matrix (ECM) supports GBM progression by promoting tumor cell proliferation, migration, and immune escape. Uridine diphosphate (UDP)-glucose 6-dehydrogenas...

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Detalles Bibliográficos
Autores principales:	Zhan, Daqian, Yalcin, Fatih, Ma, Ding, Fu, Yi, Wei, Shuang, Lal, Bachchu, Li, Yunqing, Dzaye, Omar, Laterra, John, Ying, Mingyao, Lopez-Bertoni, Hernando, Xia, Shuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chongqing Medical University 2021
Materias:	Research Watch
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243400/ https://www.ncbi.nlm.nih.gov/pubmed/35782977 http://dx.doi.org/10.1016/j.gendis.2021.08.008

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