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Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net)
Opioid Overdose Network is an effort to generalize and adapt an existing research data network, the Accrual to Clinical Trials (ACT) Network, to support design of trials for survivors of opioid overdoses presenting to emergency departments (ED). Four institutions (Medical University of South Carolin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243402/ https://www.ncbi.nlm.nih.gov/pubmed/35783072 http://dx.doi.org/10.1093/jamiaopen/ooac055 |
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author | Lenert, Leslie A Zhu, Vivienne Jennings, Lindsey McCauley, Jenna L Obeid, Jihad S Ward, Ralph Hassanpour, Saeed Marsch, Lisa A Hogarth, Michael Shipman, Perry Harris, Daniel R Talbert, Jeffery C |
author_facet | Lenert, Leslie A Zhu, Vivienne Jennings, Lindsey McCauley, Jenna L Obeid, Jihad S Ward, Ralph Hassanpour, Saeed Marsch, Lisa A Hogarth, Michael Shipman, Perry Harris, Daniel R Talbert, Jeffery C |
author_sort | Lenert, Leslie A |
collection | PubMed |
description | Opioid Overdose Network is an effort to generalize and adapt an existing research data network, the Accrual to Clinical Trials (ACT) Network, to support design of trials for survivors of opioid overdoses presenting to emergency departments (ED). Four institutions (Medical University of South Carolina [MUSC], Dartmouth Medical School [DMS], University of Kentucky [UK], and University of California San Diego [UCSD]) worked to adapt the ACT network. The approach that was taken to enhance the ACT network focused on 4 activities: cloning and extending the ACT infrastructure, developing an e-phenotype and corresponding registry, developing portable natural language processing tools to enhance data capture, and developing automated documentation templates to enhance extended data capture. Overall, initial results suggest that tailoring of existing multipurpose federated research networks to specific tasks is feasible; however, substantial efforts are required for coordination of the subnetwork and development of new tools for extension of available data. The initial output of the project was a new approach to decision support for the prescription of naloxone for home use in the ED, which is under further study within the network. |
format | Online Article Text |
id | pubmed-9243402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-92434022022-07-01 Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) Lenert, Leslie A Zhu, Vivienne Jennings, Lindsey McCauley, Jenna L Obeid, Jihad S Ward, Ralph Hassanpour, Saeed Marsch, Lisa A Hogarth, Michael Shipman, Perry Harris, Daniel R Talbert, Jeffery C JAMIA Open Case Report Opioid Overdose Network is an effort to generalize and adapt an existing research data network, the Accrual to Clinical Trials (ACT) Network, to support design of trials for survivors of opioid overdoses presenting to emergency departments (ED). Four institutions (Medical University of South Carolina [MUSC], Dartmouth Medical School [DMS], University of Kentucky [UK], and University of California San Diego [UCSD]) worked to adapt the ACT network. The approach that was taken to enhance the ACT network focused on 4 activities: cloning and extending the ACT infrastructure, developing an e-phenotype and corresponding registry, developing portable natural language processing tools to enhance data capture, and developing automated documentation templates to enhance extended data capture. Overall, initial results suggest that tailoring of existing multipurpose federated research networks to specific tasks is feasible; however, substantial efforts are required for coordination of the subnetwork and development of new tools for extension of available data. The initial output of the project was a new approach to decision support for the prescription of naloxone for home use in the ED, which is under further study within the network. Oxford University Press 2022-06-30 /pmc/articles/PMC9243402/ /pubmed/35783072 http://dx.doi.org/10.1093/jamiaopen/ooac055 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the American Medical Informatics Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lenert, Leslie A Zhu, Vivienne Jennings, Lindsey McCauley, Jenna L Obeid, Jihad S Ward, Ralph Hassanpour, Saeed Marsch, Lisa A Hogarth, Michael Shipman, Perry Harris, Daniel R Talbert, Jeffery C Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title | Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title_full | Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title_fullStr | Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title_full_unstemmed | Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title_short | Enhancing research data infrastructure to address the opioid epidemic: the Opioid Overdose Network (O2-Net) |
title_sort | enhancing research data infrastructure to address the opioid epidemic: the opioid overdose network (o2-net) |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243402/ https://www.ncbi.nlm.nih.gov/pubmed/35783072 http://dx.doi.org/10.1093/jamiaopen/ooac055 |
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