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RBM20, a Therapeutic Target to Alleviate Myocardial Stiffness via Titin Isoforms Switching in HFpEF

Increased myocardial stiffness is critically involved in heart diseases with impaired cardiac compliance, especially heart failure with preserved ejection fraction (HFpEF). Myocardial stiffness mainly derives from cardiomyocyte- and extracellular matrix (ECM)-derived passive stiffness. Titin, a majo...

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Detalles Bibliográficos
Autores principales:	Li, Na, Hang, Weijian, Shu, Hongyang, Zhou, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243441/ https://www.ncbi.nlm.nih.gov/pubmed/35783855 http://dx.doi.org/10.3389/fcvm.2022.928244

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