Cargando…
Xenotransplantation of Genetically Modified Neonatal Pig Islets Cures Diabetes in Baboons
Xenotransplantation using porcine donors is rapidly approaching clinical applicability as an alternative therapy for treatment of many end-stage diseases including type 1 diabetes. Porcine neonatal islet cell clusters (NICC) have normalised blood sugar levels for relatively short periods in the prec...
Autores principales: | Hawthorne, Wayne J., Salvaris, Evelyn J., Chew, Yi Vee, Burns, Heather, Hawkes, Joanne, Barlow, Helen, Hu, Min, Lew, Andrew M., Nottle, Mark B., O’Connell, Philip J., Cowan, Peter J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243461/ https://www.ncbi.nlm.nih.gov/pubmed/35784286 http://dx.doi.org/10.3389/fimmu.2022.898948 |
Ejemplares similares
-
Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons
por: Hawthorne, W J, et al.
Publicado: (2014) -
Targeted insertion of an anti-CD2 monoclonal antibody transgene into the GGTA1 locus in pigs using FokI-dCas9
por: Nottle, Mark B., et al.
Publicado: (2017) -
Characterizing the Mechanistic Pathways of the Instant Blood-Mediated Inflammatory Reaction in Xenogeneic Neonatal Islet Cell Transplantation
por: Liuwantara, David, et al.
Publicado: (2016) -
World first pig‐to‐human cardiac xenotransplantation
por: Hawthorne, Wayne J.
Publicado: (2022) -
Perioperative Telemetric Monitoring in Pig-to-Baboon Heterotopic Thoracic Cardiac Xenotransplantation
por: Längin, Matthias, et al.
Publicado: (2018)