Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study

Our study aims to evaluate the role of neutrophil gelatinase associated lipocalin (NGAL) as an early surrogate marker in predicting acute kidney injury (AKI) and mortality in cardiac ICU patients. The study was conducted at SRN Hospital, excluding those with known renal diseases. Out of 152 patients...

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Autores principales: Bhardwaj, Anubhuti, Narain, Upma, Gupta, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243608/
https://www.ncbi.nlm.nih.gov/pubmed/35331722
http://dx.doi.org/10.1016/j.ihj.2022.03.004
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author Bhardwaj, Anubhuti
Narain, Upma
Gupta, Arvind
author_facet Bhardwaj, Anubhuti
Narain, Upma
Gupta, Arvind
author_sort Bhardwaj, Anubhuti
collection PubMed
description Our study aims to evaluate the role of neutrophil gelatinase associated lipocalin (NGAL) as an early surrogate marker in predicting acute kidney injury (AKI) and mortality in cardiac ICU patients. The study was conducted at SRN Hospital, excluding those with known renal diseases. Out of 152 patients, 56 developed AKI (cases) and 96 were our controls. Higher NGAL was associated with increased mortality rates (P = 0.0201 and 0.0255 for serum and urinary NGAL respectively). Our study concluded that NGAL measurement at admission may be a boon in improving the outcome of cardiac ICU patients.
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spelling pubmed-92436082022-07-01 Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study Bhardwaj, Anubhuti Narain, Upma Gupta, Arvind Indian Heart J Research Brief Our study aims to evaluate the role of neutrophil gelatinase associated lipocalin (NGAL) as an early surrogate marker in predicting acute kidney injury (AKI) and mortality in cardiac ICU patients. The study was conducted at SRN Hospital, excluding those with known renal diseases. Out of 152 patients, 56 developed AKI (cases) and 96 were our controls. Higher NGAL was associated with increased mortality rates (P = 0.0201 and 0.0255 for serum and urinary NGAL respectively). Our study concluded that NGAL measurement at admission may be a boon in improving the outcome of cardiac ICU patients. Elsevier 2022 2022-03-21 /pmc/articles/PMC9243608/ /pubmed/35331722 http://dx.doi.org/10.1016/j.ihj.2022.03.004 Text en © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Bhardwaj, Anubhuti
Narain, Upma
Gupta, Arvind
Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title_full Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title_fullStr Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title_full_unstemmed Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title_short Prognostic utility of neutrophil gelatinase associated lipocalin in cardiac ICU: A prospective study
title_sort prognostic utility of neutrophil gelatinase associated lipocalin in cardiac icu: a prospective study
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243608/
https://www.ncbi.nlm.nih.gov/pubmed/35331722
http://dx.doi.org/10.1016/j.ihj.2022.03.004
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