Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting

A cross-sectional study was conducted to predict time in therapeutic range (TTR) using clinical history, examination, and socioeconomic data. Study included warfarin-receiving patients from outpatient-clinic. In 203 patients studied, mean warfarin start-dose was 2.55 mg/day and maintenance-dose/week...

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Autores principales: Anand, Aishwarya, Kumar, Rupesh, Gupta, Ankur, Vijayvergiya, Rajesh, Mehrotra, Saurabh, Lad, Deepesh, Barwad, Parag, Sharma, Swati, Patil, Amol N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243612/
https://www.ncbi.nlm.nih.gov/pubmed/35346664
http://dx.doi.org/10.1016/j.ihj.2022.03.008
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author Anand, Aishwarya
Kumar, Rupesh
Gupta, Ankur
Vijayvergiya, Rajesh
Mehrotra, Saurabh
Lad, Deepesh
Barwad, Parag
Sharma, Swati
Patil, Amol N.
author_facet Anand, Aishwarya
Kumar, Rupesh
Gupta, Ankur
Vijayvergiya, Rajesh
Mehrotra, Saurabh
Lad, Deepesh
Barwad, Parag
Sharma, Swati
Patil, Amol N.
author_sort Anand, Aishwarya
collection PubMed
description A cross-sectional study was conducted to predict time in therapeutic range (TTR) using clinical history, examination, and socioeconomic data. Study included warfarin-receiving patients from outpatient-clinic. In 203 patients studied, mean warfarin start-dose was 2.55 mg/day and maintenance-dose/week was 30.79 mg. Body mass index (BMI) (p = 0.03), warfarin maintenance dose/day (p = 0.02), and comorbidity presence (p = 0.04) were significantly associated with TTR. Occupation (p = 0.53), income (p = 0.83), education (p = 0.55), and socioeconomic score (p = 0.73) showed non-significant association with TTR. A TTR predicting nomogram was built from clinical history and examination findings.
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spelling pubmed-92436122022-07-01 Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting Anand, Aishwarya Kumar, Rupesh Gupta, Ankur Vijayvergiya, Rajesh Mehrotra, Saurabh Lad, Deepesh Barwad, Parag Sharma, Swati Patil, Amol N. Indian Heart J Research Brief A cross-sectional study was conducted to predict time in therapeutic range (TTR) using clinical history, examination, and socioeconomic data. Study included warfarin-receiving patients from outpatient-clinic. In 203 patients studied, mean warfarin start-dose was 2.55 mg/day and maintenance-dose/week was 30.79 mg. Body mass index (BMI) (p = 0.03), warfarin maintenance dose/day (p = 0.02), and comorbidity presence (p = 0.04) were significantly associated with TTR. Occupation (p = 0.53), income (p = 0.83), education (p = 0.55), and socioeconomic score (p = 0.73) showed non-significant association with TTR. A TTR predicting nomogram was built from clinical history and examination findings. Elsevier 2022 2022-03-25 /pmc/articles/PMC9243612/ /pubmed/35346664 http://dx.doi.org/10.1016/j.ihj.2022.03.008 Text en © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Anand, Aishwarya
Kumar, Rupesh
Gupta, Ankur
Vijayvergiya, Rajesh
Mehrotra, Saurabh
Lad, Deepesh
Barwad, Parag
Sharma, Swati
Patil, Amol N.
Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title_full Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title_fullStr Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title_full_unstemmed Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title_short Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
title_sort development of an interview-based warfarin nomogram predicting the time spent in the therapeutic inr range: a cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243612/
https://www.ncbi.nlm.nih.gov/pubmed/35346664
http://dx.doi.org/10.1016/j.ihj.2022.03.008
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