Human cytomegalovirus RNA2.7 inhibits RNA polymerase II (Pol II) Serine-2 phosphorylation by reducing the interaction between Pol II and phosphorylated cyclin-dependent kinase 9 (pCDK9)

Human cytomegalovirus (HCMV) is a ubiquitous pathogen belongs to betaherpesvirus subfamily. RNA2.7 is a highly conserved long non-coding RNA accounting for more than 20% of total viral transcripts. In our study, functions of HCMV RNA2.7 were investigated by comparison of host cellular transcriptomes...

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Detalles Bibliográficos
Autores principales: Huang, Yujing, Guo, Xin, Zhang, Jing, Li, Jianming, Xu, Mingyi, Wang, Qing, Liu, Zhongyang, Ma, Yanping, Qi, Ying, Ruan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243627/
https://www.ncbi.nlm.nih.gov/pubmed/35537980
http://dx.doi.org/10.1016/j.virs.2022.02.011

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