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Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics

Single-cell proteomics has the potential to decipher tumor heterogeneity, and a method like single-cell proteomics by mass spectrometry (SCoPE-MS) allows profiling several tens of single cells for >1,000 proteins per cell. This method, however, cannot link the proteome of individual cells with ph...

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Detalles Bibliográficos
Autores principales: Su, Pin-Rui, You, Li, Beerens, Cecile, Bezstarosti, Karel, Demmers, Jeroen, Pabst, Martin, Kanaar, Roland, Hsu, Cheng-Chih, Chien, Miao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243628/
https://www.ncbi.nlm.nih.gov/pubmed/35784653
http://dx.doi.org/10.1016/j.crmeth.2022.100237

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