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Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics
Single-cell proteomics has the potential to decipher tumor heterogeneity, and a method like single-cell proteomics by mass spectrometry (SCoPE-MS) allows profiling several tens of single cells for >1,000 proteins per cell. This method, however, cannot link the proteome of individual cells with ph...
Autores principales: | Su, Pin-Rui, You, Li, Beerens, Cecile, Bezstarosti, Karel, Demmers, Jeroen, Pabst, Martin, Kanaar, Roland, Hsu, Cheng-Chih, Chien, Miao-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243628/ https://www.ncbi.nlm.nih.gov/pubmed/35784653 http://dx.doi.org/10.1016/j.crmeth.2022.100237 |
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