Overcoming the LAG3 phase problem

Lymphocyte activation gene 3 (LAG3) is an important checkpoint inhibitor molecule of immunotherapeutic interest. New crystal structures of LAG3 provide important insight into its molecular architecture, laying the groundwork for future basic and applied investigations.

Detalles Bibliográficos
Autores principales: Petersen, Jan, Rossjohn, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243723/
https://www.ncbi.nlm.nih.gov/pubmed/35761086
http://dx.doi.org/10.1038/s41590-022-01239-6
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author Petersen, Jan
Rossjohn, Jamie
author_facet Petersen, Jan
Rossjohn, Jamie
author_sort Petersen, Jan
collection PubMed
description Lymphocyte activation gene 3 (LAG3) is an important checkpoint inhibitor molecule of immunotherapeutic interest. New crystal structures of LAG3 provide important insight into its molecular architecture, laying the groundwork for future basic and applied investigations.
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spelling pubmed-92437232022-06-30 Overcoming the LAG3 phase problem Petersen, Jan Rossjohn, Jamie Nat Immunol News & Views Lymphocyte activation gene 3 (LAG3) is an important checkpoint inhibitor molecule of immunotherapeutic interest. New crystal structures of LAG3 provide important insight into its molecular architecture, laying the groundwork for future basic and applied investigations. Nature Publishing Group US 2022-06-27 2022 /pmc/articles/PMC9243723/ /pubmed/35761086 http://dx.doi.org/10.1038/s41590-022-01239-6 Text en © Springer Nature America, Inc. 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle News & Views
Petersen, Jan
Rossjohn, Jamie
Overcoming the LAG3 phase problem
title Overcoming the LAG3 phase problem
title_full Overcoming the LAG3 phase problem
title_fullStr Overcoming the LAG3 phase problem
title_full_unstemmed Overcoming the LAG3 phase problem
title_short Overcoming the LAG3 phase problem
title_sort overcoming the lag3 phase problem
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243723/
https://www.ncbi.nlm.nih.gov/pubmed/35761086
http://dx.doi.org/10.1038/s41590-022-01239-6
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