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Overcoming the LAG3 phase problem
Lymphocyte activation gene 3 (LAG3) is an important checkpoint inhibitor molecule of immunotherapeutic interest. New crystal structures of LAG3 provide important insight into its molecular architecture, laying the groundwork for future basic and applied investigations.
Autores principales: | Petersen, Jan, Rossjohn, Jamie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243723/ https://www.ncbi.nlm.nih.gov/pubmed/35761086 http://dx.doi.org/10.1038/s41590-022-01239-6 |
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