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Liver transplantation in hepatic myelopathy
Hepatic myelopathy (HMy) is a rare neurological complication of liver cirrhosis that involves spastic paraplegia caused by lateral cord demyelination especially due to the accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and par...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243758/ https://www.ncbi.nlm.nih.gov/pubmed/35783476 http://dx.doi.org/10.14744/hf.2021.2021.0004 |
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author | Acar, Sencan Dinckan, Ayhan Akyildiz, Murat |
author_facet | Acar, Sencan Dinckan, Ayhan Akyildiz, Murat |
author_sort | Acar, Sencan |
collection | PubMed |
description | Hepatic myelopathy (HMy) is a rare neurological complication of liver cirrhosis that involves spastic paraplegia caused by lateral cord demyelination especially due to the accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and paraparesis in extremities after intrahepatic portosystemic shunting (TIPS) application and underwent deceased liver transplantation (LT). A 39-year-old woman underwent deceased LT because of cryptogenic liver cirrhosis. She underwent a TIPS procedure 5 years ago. After that, hepatic encephalopathy and spasticity appeared. She was on the waiting list for 3 years. Neurological findings after LT significantly decreased, but did not return to normal. After the emergence of neurological findings, the earlier LT can provide improvement in neurological findings. |
format | Online Article Text |
id | pubmed-9243758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-92437582022-07-01 Liver transplantation in hepatic myelopathy Acar, Sencan Dinckan, Ayhan Akyildiz, Murat Hepatol Forum Case Report - LT in hepatic myelopathy Hepatic myelopathy (HMy) is a rare neurological complication of liver cirrhosis that involves spastic paraplegia caused by lateral cord demyelination especially due to the accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and paraparesis in extremities after intrahepatic portosystemic shunting (TIPS) application and underwent deceased liver transplantation (LT). A 39-year-old woman underwent deceased LT because of cryptogenic liver cirrhosis. She underwent a TIPS procedure 5 years ago. After that, hepatic encephalopathy and spasticity appeared. She was on the waiting list for 3 years. Neurological findings after LT significantly decreased, but did not return to normal. After the emergence of neurological findings, the earlier LT can provide improvement in neurological findings. Kare Publishing 2022-04-26 /pmc/articles/PMC9243758/ /pubmed/35783476 http://dx.doi.org/10.14744/hf.2021.2021.0004 Text en © Copyright 2022 by Hepatology Forum - Available online at www.hepatologyforum.org https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
spellingShingle | Case Report - LT in hepatic myelopathy Acar, Sencan Dinckan, Ayhan Akyildiz, Murat Liver transplantation in hepatic myelopathy |
title | Liver transplantation in hepatic myelopathy |
title_full | Liver transplantation in hepatic myelopathy |
title_fullStr | Liver transplantation in hepatic myelopathy |
title_full_unstemmed | Liver transplantation in hepatic myelopathy |
title_short | Liver transplantation in hepatic myelopathy |
title_sort | liver transplantation in hepatic myelopathy |
topic | Case Report - LT in hepatic myelopathy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243758/ https://www.ncbi.nlm.nih.gov/pubmed/35783476 http://dx.doi.org/10.14744/hf.2021.2021.0004 |
work_keys_str_mv | AT acarsencan livertransplantationinhepaticmyelopathy AT dinckanayhan livertransplantationinhepaticmyelopathy AT akyildizmurat livertransplantationinhepaticmyelopathy |