Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence

Treatment options for various rheumatologic diseases have been limited until the introduction of biologic agents and kinase inhibitor therapy in recent decades. Since their arrival, they have steadily been integrated into routine management. Given their wide use and overall successful outcomes, it b...

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Autores principales: Bhandari, Sambhawana, Baral, Maun Ranjan, Barbery, Matthew, Rudinskaya, Alla, Sostin, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243812/
https://www.ncbi.nlm.nih.gov/pubmed/35759025
http://dx.doi.org/10.1007/s00277-022-04896-7
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author Bhandari, Sambhawana
Baral, Maun Ranjan
Barbery, Matthew
Rudinskaya, Alla
Sostin, Oleg
author_facet Bhandari, Sambhawana
Baral, Maun Ranjan
Barbery, Matthew
Rudinskaya, Alla
Sostin, Oleg
author_sort Bhandari, Sambhawana
collection PubMed
description Treatment options for various rheumatologic diseases have been limited until the introduction of biologic agents and kinase inhibitor therapy in recent decades. Since their arrival, they have steadily been integrated into routine management. Given their wide use and overall successful outcomes, it becomes increasingly pertinent for clinicians to readily identify their side effects. Their effects can involve multiple organ systems, including hematologic. This review aims to identify and classify the range of hematologic effects associated with individual biologics and kinase inhibitors used for treatment of rheumatologic diseases.
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spelling pubmed-92438122022-06-30 Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence Bhandari, Sambhawana Baral, Maun Ranjan Barbery, Matthew Rudinskaya, Alla Sostin, Oleg Ann Hematol Review Article Treatment options for various rheumatologic diseases have been limited until the introduction of biologic agents and kinase inhibitor therapy in recent decades. Since their arrival, they have steadily been integrated into routine management. Given their wide use and overall successful outcomes, it becomes increasingly pertinent for clinicians to readily identify their side effects. Their effects can involve multiple organ systems, including hematologic. This review aims to identify and classify the range of hematologic effects associated with individual biologics and kinase inhibitors used for treatment of rheumatologic diseases. Springer Berlin Heidelberg 2022-06-27 2022 /pmc/articles/PMC9243812/ /pubmed/35759025 http://dx.doi.org/10.1007/s00277-022-04896-7 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Bhandari, Sambhawana
Baral, Maun Ranjan
Barbery, Matthew
Rudinskaya, Alla
Sostin, Oleg
Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title_full Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title_fullStr Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title_full_unstemmed Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title_short Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
title_sort hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9243812/
https://www.ncbi.nlm.nih.gov/pubmed/35759025
http://dx.doi.org/10.1007/s00277-022-04896-7
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