Development of an immunogen containing CD4(+)/CD8(+) T-cell epitopes for the prophylaxis of tegumentary leishmaniasis

ABSTRACT: Tegumentary leishmaniasis (TL) is a disease of high severity and incidence in Brazil, and Leishmania braziliensis is its main etiological agent. The inefficiency of control measures, such as high toxicity and costs of current treatments and the lack of effective immunoprophylactic strategi...

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Detalles Bibliográficos
Autores principales: de Andrade Ferraz, Isabela, Carvalho, Ana Maria Ravena Severino, de Brito, Rory Cristiane Fortes, Roatt, Bruno Mendes, Martins, Vívian Tamietti, Lage, Daniela Pagliara, dos Reis Cruz, Luiza, Medeiros, Fernanda Alvarenga Cardoso, Gonçalves, Denise Utsch, da Costa Rocha, Manoel Otávio, Coelho, Eduardo Antonio Ferraz, de Oliveira Mendes, Tiago Antônio, Duarte, Mariana Costa, Menezes-Souza, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Applied Genetics and Molecular Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244519/
https://www.ncbi.nlm.nih.gov/pubmed/35759035
http://dx.doi.org/10.1007/s00253-022-12033-7

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