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Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy

Primary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever...

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Autores principales: Chen, Panpan, Hao, Yuanyuan, Qiu, Xi, Xiao, Xibin, Zhu, Wei, Xu, Yang, Qian, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244709/
https://www.ncbi.nlm.nih.gov/pubmed/35784303
http://dx.doi.org/10.3389/fimmu.2022.890059
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author Chen, Panpan
Hao, Yuanyuan
Qiu, Xi
Xiao, Xibin
Zhu, Wei
Xu, Yang
Qian, Wenbin
author_facet Chen, Panpan
Hao, Yuanyuan
Qiu, Xi
Xiao, Xibin
Zhu, Wei
Xu, Yang
Qian, Wenbin
author_sort Chen, Panpan
collection PubMed
description Primary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever, syncope, palpitations, and a third-degree atrioventricular block (AVB) on electrocardiogram. Chemotherapy was administered with two courses of methotrexate, cyclophosphamide, liposomal doxorubicin, vincristine, and dexamethasone (MTX-CHOP). As the tumor vanished, AVB changed from third degree to second degree and finally to sinus rhythm. In conclusion, endomyocardial biopsy is valuable in the diagnosis of primary cardiac lymphoma. It is worth noting that alterations in the electrocardiogram may indicate an attack on the heart by PCTL.
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spelling pubmed-92447092022-07-01 Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy Chen, Panpan Hao, Yuanyuan Qiu, Xi Xiao, Xibin Zhu, Wei Xu, Yang Qian, Wenbin Front Immunol Immunology Primary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever, syncope, palpitations, and a third-degree atrioventricular block (AVB) on electrocardiogram. Chemotherapy was administered with two courses of methotrexate, cyclophosphamide, liposomal doxorubicin, vincristine, and dexamethasone (MTX-CHOP). As the tumor vanished, AVB changed from third degree to second degree and finally to sinus rhythm. In conclusion, endomyocardial biopsy is valuable in the diagnosis of primary cardiac lymphoma. It is worth noting that alterations in the electrocardiogram may indicate an attack on the heart by PCTL. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9244709/ /pubmed/35784303 http://dx.doi.org/10.3389/fimmu.2022.890059 Text en Copyright © 2022 Chen, Hao, Qiu, Xiao, Zhu, Xu and Qian https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Chen, Panpan
Hao, Yuanyuan
Qiu, Xi
Xiao, Xibin
Zhu, Wei
Xu, Yang
Qian, Wenbin
Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title_full Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title_fullStr Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title_full_unstemmed Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title_short Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
title_sort case report: primary cardiac t-cell lymphoma with complete atrio-ventricular block diagnosed by endomyocardial biopsy
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244709/
https://www.ncbi.nlm.nih.gov/pubmed/35784303
http://dx.doi.org/10.3389/fimmu.2022.890059
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