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Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue

Sustained complement activation is an underlying pathologic driver in many inflammatory and autoimmune diseases. Currently approved anti-complement therapies are directed at the systemic blockade of complement. Consequently, these therapies provide widespread inhibition of complement pathway activit...

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Detalles Bibliográficos
Autores principales:	Fahnoe, Kelly C., Liu, Fei, Morgan, Jennifer G., Ryan, Sarah T., Storek, Michael, Stark, Ellen Garber, Taylor, Fred R., Holers, V. Michael, Thurman, Joshua M., Wawersik, Stefan, Kalled, Susan L., Violette, Shelia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244803/ https://www.ncbi.nlm.nih.gov/pubmed/35784298 http://dx.doi.org/10.3389/fimmu.2022.869725

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