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Albumin-mediated extracellular zinc speciation drives cellular zinc uptake
The role of the extracellular medium in influencing metal uptake into cells has not been described quantitatively. In a chemically-defined model system containing albumin, zinc influx into endothelial cells correlates with the extracellular free zinc concentration. Allosteric inhibition of zinc-bind...
Autores principales: | Coverdale, James P. C., van den Berg, Hugo A., Khazaipoul, Siavash, Bridgewater, Hannah E., Stewart, Alan J., Blindauer, Claudia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244874/ https://www.ncbi.nlm.nih.gov/pubmed/35695483 http://dx.doi.org/10.1039/d2cc02278h |
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